Five keys to the game for when the 49ers play the Rams this weekend.

49ers vs Rams Week 18

1

Kittle is all-world vs all-pro when he's healthy. Right now he's healthy and delivering incredible game stats seemingly at will. Kittle needs to be contained. Somehow.

George Kittle

2

Last week Matthew Stafford threw for 309 yards, 8.8 YPA, 2 TDs, and 2 INTs. He hooked up with OBJ late to get the come-from-behind victory but he has not been solid lately. As he goes, so go the LA Rams.

Matthew Stafford

3

In week 17 Trey Lance threw for 2 TDs, a 10.8 YPA, and a 116 QBR. Starting out very conservative he warmed up. Jimmy Garappolo has a bum thumb right now and it's a toss-up as to who starts. Rams D doesn't care.

49ers QB

4

Against the Vikings Kupp got 7 targets, hauled in 6 receptions for 95 yards and a touchdown. Typical.  Stafford to OBJ is exciting. Stafford to Kupp is critical.

Cooper Kupp

5

The Niners' pass defense held Matthew Stafford in week 10 to 243 yards, 1 TD, 2 INT, and a 67.5 QBR. That's winning football and if they can frazzle Stafford again this week it's Niners victory all the way.

49ers Pass D

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Bonus

You can't mention the Rams without mentioning Aaron Donald. It's such a given you can overlook him. BIG mistake. He will make a difference on game day.

Bonus Key

Bonus

In week 10 Deebo Samuel exploded for 97 receiving yards, 1 receiving TD, and 1 rushing TD. Yeah, he is all that and you better have a game plan to stop him.

Wildcard